This article aims to translate and revise the Digital Stress Scale (DSS) developed by Hall et al. (2021) and validate the revised Chinese DSS’s reliability and validity among Chinese college students. Structured interviews regarding social media use and digital stress were conducted with 15 Chinese college students in sample 1. Four other samples of Chinese college students (n=87, n=100, n=300, n=239) were recruited online by convenience sampling. Item analysis, confirmatory factor analysis, construct validity, criterion-related validity and reliability analysis were conducted. Depression-Anxiety-Stress scale, life satisfaction, UCLA loneliness scale, perceived social support and Bergen Social Media Addiction Scale were used to assess criterion-related validity. Test-retest validity was assessed among 156 college students in sample five two weeks after baseline. The revised Chinese Digital Stress Scale (RC-DSS) consists of 31 items, including six dimensions (availability stress, approval anxiety, social comparison, fear of missing out, connection overload and online vigilance). Discrimination analysis and item analysis showed good discriminability. The six-dimension structure of the scale was confirmed by confirmatory factor analysis (χ2/df=2.82, GFI=0.80, NFI=0.93, TLI=0.95, CFI=0.96, RMSEA=0.08). Digital stress was significantly and moderately associated with social media addiction, stress, depression, anxiety and loneliness (rs=0.41–0.61, ps<0.01), and was negatively associated with social support and life satisfaction (r = −0.24, p<0.01; r = −0.15, p<0.05). The Cronbach’s alpha of the scale was 0.94 and its two-week test-retest reliability was 0.73 (p<0.01). The RC-DSS is a reliable and valid instrument to assess digital stress among Chinese college students.