Shishan in the city of Foshan and Songshanhu in the city of Dongguan in the Pearl River Delta are typical examples of integration of towns and industrial zones and dynamic mechanism of urbanization. Based on land use data of 2015 in Guangdong Province and the socioeconomic data of 2016 in two cities, the study examines the attributes, patterns, and mechanisms of the integration from the perspective of governance and has four findings. 1) Integration of industrial zones and towns is a form of urban-industrial integration at the scale of villages and towns, and its connotation includes institutional integration, spatial and functional integration, and urbanization. 2) Shishan adopts a gradual renewal of the integration of industrial zones and towns, and forms a spatial structure of the core that drives the development of the periphery. Songshanhu adopts the development model of planning the entire zone and town to form multiple functions of subzones. 3) The zone-town system is affected by internal and external forces. The external forces include globalization, land finance, and national and regional policy adjustment. As coordinating force, development force, and supporting force, the three pivotal elements of institution, industry, and urbanization function promote the integration. 4) As the key actor of the main external power, local governments lead the development of integration. Shishan restructs the system, industry and urbanization at the town scale, and gradually integrates them; Songshanhu deploys the localization of institution and industries to promote the integration. As a result, both Shishan and Songshanhu have transformed the previous development model of villages and towns in the Pearl River Delta, and promots the integration of towns and development zones.