The REE data in literature for garnet in skarn deposits are compiled to discuss main factors affecting the REE partition. The data shows that the garnet in skarn deposit is mainly grossular-andradite garnet. From the andradite to grossular, the garnet changes from LREE-enriched to HREE-enriched. In the LREE enriched type, with the decrease of andradite, the highest point in REE distribution diagram change from La-Ce through Ce-Pr to Pr-Nd. The statistic data show that the main factor affecting the REE pattern is the major composition of the garnet. The REE pattern of hydrothermal fluid and the other factors have little affection. REE usually enter dodecahedral site in garnet. With the increase of andradite, ideal radius of dodecahedral site increase accordingly, and garnet displays LREE-enriched and HREE-depleted features, for the larger ion radius of LREE than HREE. In the deposit with positive Eu anomaly fluid, most garnet also show positive Eu anomaly. The depletion of oxygen fugacity or increasing of salinity will elevate the Eu positive anomaly. Whereas the crystallization and dissolution of Eu enriched minerals can deplete and elevate Eu positive anomaly in hydrothermal fluid respectively. Then the hydrothermal fluid subsequently affects the garnet Eu anomaly character. As a result, the Eu anomaly of the garnet can be used to trace the salinity and oxygen fugacity of the hydrothermal fluids and the Eu enriched mineral dissolution or precipitation.