脑动静脉畸形栓塞时急性脑出血的血液动力学因素分析

北京大学学报（自然科学版）

脑动静脉畸形栓塞时急性脑出血的血液动力学因素分析

孙树津¹,严宗毅¹,王大明²,凌锋³

¹北京大学力学与工程科学系，北京，100871；²卫生部北京医院神经外科，北京，100730；³首都医科大学宣武医院神经外科，北京，100053

收稿日期:2000-09-18 出版日期:2001-09-20 发布日期:2001-09-20

Hemodynamics Factor in Acute Intracranial Hemorrhage Occuring when Cerebral AVM is Embolized

SUN Shujin¹，YAN Zongyi¹, WANG Daming², LING Feng³

¹Department of Mechanics and Engineering Science, Peking University, Beijing, 100871; ²Center of Interventional Neuroradiology, Beijing Hospital, Beijing, 100730; ³Department of Neurosurgery, Xuan Wu Hospital, Capital Medical University, Beijing, 100053

Received:2000-09-18 Online:2001-09-20 Published:2001-09-20

摘要/Abstract

摘要： 以水击原理分析了脑AVM栓塞治疗时血液动力学变化过程，计算了瞬时水击压力可能达到的最高值。瞬时增高的水击压力可能是AVM栓塞时发生急性脑出血或脑肿胀的重要血液动力学因素。而AVM供血动脉血管壁面切应力偏高和供血动脉过长可增加水击的危险程度，提示对这类结构AVM栓塞治疗时应采取合理的降压措施并尽可能分多次栓塞。

关键词: 脑动静脉畸形, 水击, 栓塞, 血液动力学, 急性脑内出血

Abstract: The hemodynamic change induced by embolization of the cerebral arteriovenous malformation(AVM) was analyzed using the Water Hammer principle. The highest pressure that can be reached when the water hammer phenomenon occurs was calculated. The acute instantaneous pressure rising may be an important factor leading to intracranial hemorrhage or swelling when the AVM is embolized. It is shown that long feeding artery of AVM will increase the possibility of direct water hammer, and high wall shear stress of feeding artery will increase the water hammer pressure. This suggests that such kind of AVMs should be embolized stepwise and the systemic pressure should be rationally reduced before embolization.

Key words: cerebral arteriovenous malformation(AVM), water hammer, embolization, hemodynamics, acute intracranial hemorrhage

中图分类号:

R318.01
Q666

孙树津,严宗毅,王大明,凌锋. 脑动静脉畸形栓塞时急性脑出血的血液动力学因素分析[J]. 北京大学学报（自然科学版）.

SUN Shujin,YAN Zongyi,WANG Daming,LING Feng. Hemodynamics Factor in Acute Intracranial Hemorrhage Occuring when Cerebral AVM is Embolized[J]. Acta Scientiarum Naturalium Universitatis Pekinensis.

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链接本文: https://xbna.pku.edu.cn/CN/

https://xbna.pku.edu.cn/CN/Y2001/V37/I5/679

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