关键词: 弯曲血管, 大分子传质, 二次流

Abstract: The transport of macromolecules in curved tubes with permeable arterial wall was simulated numerically. The fields of axial velocity, the fields of secondary flow function and the distribution of wall shear stress along the transverse section of arterial wall were obtained under different Dean number, 10≤De≤10800. The concentration fields under different Dean number and Peclet number, 10≤De≤2 000，1≤Pe≤4，were calculated in curved tube with permeable arterial wall and effects of parameters,such as shear stress, mass flux of arterial wall, on mass transfer were studied. It was found that steady laminar flow become unsteady with the increase of De. The concentration in inner section of transverse section of the tube is higher than other areas, and with the increase of De and Pe, the concentration there increase obviously. It indicates that for the permeable arterial wall, the macromolecules are likely to gather in the areas where axial velocity and shear stress are relatively low, thus indicates why location of atherosclerosis frequently occurs at inner side of curved tube.

Key words: curved tube, the transport of macromolecules, secondary flow