关键词: 骨质疏松症, 骨吸收, 组织蛋白酶, 抑制剂, 骨质疏松症, 骨吸收, 组织蛋白酶, 抑制剂

Abstract: Osteoporosis is the most commonly occurred metabolic bone disease. Osteoporotic fractures are a major cause of morbidity and mortality in elderly populations in many parts of the world. As the coming of old age society, the prevention and treatment of osteoporosis has become an urgent problem. The cathepsin L antagonists can effectively inhibit bone resorption, so it has a good prospect of treating osteoporosis. This article reviewed the progress of antiosteoporosis research of cathepsin L antagonists.

Key words: osteoporosis, bone resorption, cathepsin, antagonist, osteoporosis, bone resorption, cathepsin, antagonist