北京大学学报(自然科学版)

酒石酸在合成手性化合物中的应用Ⅰ L-(-)-2,3-O-亚甲基苏力糖醇和L-(+)-2,3-O-亚异丙基苏力糖醇的制备

聂爱华,陈新潮,陈业忠,叶秀林   

  1. 北京大学化学与分子工程学院,北京,100871
  • 收稿日期:1997-02-24 出版日期:1997-11-20 发布日期:1997-11-20

Studies on the Application of Tartaric Acid to the Synthesis of Chiral Compounds Ⅰ The Synthesis of L-(-)-2, 3-O-methylidene Threitol and L-(+)-2, 3-O-isopropylidene Threitol

NIE Aihua, CHEN Xinchao, CHEN Yezhong, YE Xiulin   

  1. College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871
  • Received:1997-02-24 Online:1997-11-20 Published:1997-11-20

摘要: 通过较为简便的方法合成了可用于手性化合物合成的L-(-)-2,3-O-亚甲基苏力糖醇和L-(+)-2,3-O-亚异丙基苏力糖醇。

关键词: 酒石酸, 手性, 苏力糖醇, 合成

Abstract: Simple but efficient procedures were proposed for preparation of L-(-)-2, 3-O-methylidene Threitol and L-(+)-2, 3-O-isopropylidene Threitol in the present paper. It is suggested to use these two thretols as the chiral precursors of synthesizing (-)-anisomycin.

Key words: tartaric acid, L-2, 3-O-alkylidene threitols, synthesis

中图分类号: