北京大学学报（自然科学版）
王瑛1,陈来同2
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WANG Ying1, CHEN Laitong2
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关键词: 基因拷贝数, 单倍体基因组, α1-抗胰蛋白酶基因, 大鼠RALRS-1重复序列
Abstract: A modified method for the estimation of gene copy number in genome is proposed. It based upon the size ratio between the cloned gene and its haploid genome. From the size fraction and the amount of genomic DNA used for analysis, the gene copy number could be estimated from the data of dot blot or Southern blot analysis. Using the procedure proposed by this study, the copy numbers of human α1-antitrypsin gene and rat RALRS-1 repetitive sequence were determined.
Key words: gene copy number, haploid genome, human α1-antitrypsin gene, rat RALRS-1 repetitive sequence
中图分类号:
Q578
王瑛,陈来同 . 基因拷贝数分析的研究[J]. 北京大学学报（自然科学版）.
WANG Ying,CHEN Laitong. A Modified Procedure for the Determination of the Gene Copy Number[J]. Acta Scientiarum Naturalium Universitatis Pekinensis.
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链接本文: https://xbna.pku.edu.cn/CN/
https://xbna.pku.edu.cn/CN/Y1996/V32/I6/781
