Studies on the Application of Tartaric Acid to the Synthesis of Chiral Compounds Ⅰ The Synthesis of L-(-)-2, 3-O-methylidene Threitol and L-(+)-2, 3-O-isopropylidene Threitol

Acta Scientiarum Naturalium Universitatis Pekinensis

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Studies on the Application of Tartaric Acid to the Synthesis of Chiral Compounds Ⅰ The Synthesis of L-(-)-2, 3-O-methylidene Threitol and L-(+)-2, 3-O-isopropylidene Threitol

NIE Aihua, CHEN Xinchao, CHEN Yezhong, YE Xiulin

College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871

Received:1997-02-24 Online:1997-11-20 Published:1997-11-20

酒石酸在合成手性化合物中的应用Ⅰ L-(-)-2,3-O-亚甲基苏力糖醇和L-(+)-2,3-O-亚异丙基苏力糖醇的制备

聂爱华,陈新潮,陈业忠,叶秀林

北京大学化学与分子工程学院，北京，100871

Abstract

Abstract: Simple but efficient procedures were proposed for preparation of L-(-)-2, 3-O-methylidene Threitol and L-(+)-2, 3-O-isopropylidene Threitol in the present paper. It is suggested to use these two thretols as the chiral precursors of synthesizing (-)-anisomycin.

Key words: tartaric acid, L-2, 3-O-alkylidene threitols, synthesis

摘要： 通过较为简便的方法合成了可用于手性化合物合成的L-(-)-2,3-O-亚甲基苏力糖醇和L-(+)-2，3-O-亚异丙基苏力糖醇。

关键词: 酒石酸, 手性, 苏力糖醇, 合成

CLC Number:

NIE Aihua,CHEN Xinchao,CHEN Yezhong,YE Xiulin. Studies on the Application of Tartaric Acid to the Synthesis of Chiral Compounds Ⅰ The Synthesis of L-(-)-2, 3-O-methylidene Threitol and L-(+)-2, 3-O-isopropylidene Threitol[J]. Acta Scientiarum Naturalium Universitatis Pekinensis.

聂爱华,陈新潮,陈业忠,叶秀林. 酒石酸在合成手性化合物中的应用Ⅰ L-(-)-2,3-O-亚甲基苏力糖醇和L-(+)-2,3-O-亚异丙基苏力糖醇的制备[J]. 北京大学学报（自然科学版）.

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Studies on the Application of Tartaric Acid to the Synthesis of Chiral Compounds Ⅰ The Synthesis of L-(-)-2, 3-O-methylidene Threitol and L-(+)-2, 3-O-isopropylidene Threitol

酒石酸在合成手性化合物中的应用Ⅰ L-(-)-2,3-O-亚甲基苏力糖醇和L-(+)-2,3-O-亚异丙基苏力糖醇的制备

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