Acta Scientiarum Naturalium Universitatis Pekinensis

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Studies on the Constituents of Flavonoids from Craibiodendron Yunnanense

XU Baoan, SHU Ye, ZHANG Mingzhe   

  • Received:1996-04-15 Online:1996-11-20 Published:1996-11-20

金叶子黄酮类成分的研究

许宝安, 舒晔, 张明哲   

  1. 北京大学化学与分子工程学院,北京,100871;兰州大学应用有机国家重点实验室,兰州,730000

Abstract: The leaves of Craibiodendron yunnanense W.W. Smith collected from Yunnan Province were extracted by organic solvents with different polarity. After chromatography for many times and purification, six compounds were isolated for the first time from this plant. On the basis of determination of physical and chemical properties and spectral analyses they were identified as 11 α-hydroxy-α-amyrin(Ⅰ), β-sitosterol(Ⅱ), quercetin(Ⅲ),quercetin-3-O-α-arabinofuranoside(Ⅳ), quercetin-3-O-α-rhamnopyranoside(Ⅴ), quercetin-3-O-β-galactopyranoside(Ⅵ). The pharmacological verification of crude flavonoids was made preliminarily on mice, the results showed it has central inhibition.

Key words: craibiodendron yunnanense, flavonoid, quercetin, quercetinara-binofuranoside, quercetinrham-nopyranoside

摘要: 金叶子叶经不同溶剂提取、浓缩及多次层析分离,纯化后从这一植物中得到6个化合物。利用波谱和化学方法阐明其结构,计有11α-羟基-α-香树素(Ⅰ)、β-谷甾醇(Ⅱ)、槲皮素(Ⅲ)、槲皮素-3-O-α-阿拉伯呋喃糖甙(Ⅳ)、槲皮素-3-O-α-鼠李吡喃糖甙(Ⅴ)、槲皮素-3-O-β-半乳吡喃糖甙(Ⅵ)。总黄酮经小鼠的初步药理试验,表明有一定的中枢抑制作用。

关键词: 金叶子, 黄酮类化合物, 槲皮素, 槲皮素阿拉伯呋喃糖甙, 槲皮素鼠李吡喃糖甙

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