Formation of the p-Toluenesulphinyl Anion from the Diester of N-Tosyl Alanine with 2, 6-Bis(hydroxylmethyl) pyridine and Its Nucleophilic Addition Product with 2, 6-Bis(chloromethyl) pyridine

Acta Scientiarum Naturalium Universitatis Pekinensis

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Formation of the p-Toluenesulphinyl Anion from the Diester of N-Tosyl Alanine with 2, 6-Bis(hydroxylmethyl) pyridine and Its Nucleophilic Addition Product with 2, 6-Bis(chloromethyl) pyridine

CHEN Yantao，HUA Wenting

College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871

Received:2000-10-11 Online:2001-07-20 Published:2001-07-20

N-对甲苯磺酰丙氨酰-2, 6-二羟甲基吡啶双酯的消除机制及对甲苯亚磺酰离子和2，6-二甲基吡啶反应的研究

陈延涛,花文廷

北京大学化学与分子工程学院，北京，100871

Abstract

Abstract: The mechanism of the formation of 2, 6-bis(hydroxymethyl) pyridine di-p -toluenesulphinate(3) and its mass spectrum were studied in detail.

Key words: synthesis, reaction mechanism, MS, ion fragmentation

摘要： 报道了双-对甲苯磺酰丙氨酰-2, 6-二羟甲基吡啶酯在NaH作用下，生成双-对甲苯亚磺酰-2, 6-二羟甲基吡啶酯的反应条件和机理，并研究了产物的质谱碎裂机制。

关键词: 合成, 反应机制, 碎裂机理

CLC Number:

O626

CHEN Yantao,HUA Wenting. Formation of the p-Toluenesulphinyl Anion from the Diester of N-Tosyl Alanine with 2, 6-Bis(hydroxylmethyl) pyridine and Its Nucleophilic Addition Product with 2, 6-Bis(chloromethyl) pyridine[J]. Acta Scientiarum Naturalium Universitatis Pekinensis.

陈延涛,花文廷. N-对甲苯磺酰丙氨酰-2, 6-二羟甲基吡啶双酯的消除机制及对甲苯亚磺酰离子和2，6-二甲基吡啶反应的研究[J]. 北京大学学报（自然科学版）.

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Formation of the p-Toluenesulphinyl Anion from the Diester of N-Tosyl Alanine with 2, 6-Bis(hydroxylmethyl) pyridine and Its Nucleophilic Addition Product with 2, 6-Bis(chloromethyl) pyridine

N-对甲苯磺酰丙氨酰-2, 6-二羟甲基吡啶双酯的消除机制及对甲苯亚磺酰离子和2，6-二甲基吡啶反应的研究

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