Acta Scientiarum Naturalium Universitatis Pekinensis

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Synthesis of Coumarin Derivatives Using Microwave Irradiation

CHEN Xiong1, LI Chongxi1, MA Weiyong2   

  1. 1College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871; 2Shanghai Institute of Pharmaceutical Industry, Shanghai, 200437
  • Received:2001-05-30 Online:2002-03-20 Published:2002-03-20

微波辐射促进香豆素衍生物合成的研究

陈雄1, 李崇熙1, 马维勇2   

  1. 1北京大学化学与分子工程学院,北京,100871; 2上海医药工业研究院,上海,200437

Abstract: Some coumarin derivatives are synthesized through Pechmann reaction with catalytical amount of sulfuric acid. Microwave irradiation is used and moderate to excellent results are got. The method is also very fast and convenient.

Key words: microwave irradiation, Pechmann reaction, coumarin derivatives

摘要: 在催化量硫酸的存在下,用微波辐射进行Pechmann反应,制备香豆素衍生物,获得中等至良好的产率。本方法快速、方便。

关键词: 微波辐射, Pechmann反应, 香豆素衍生物

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