Acta Scientiarum Naturalium Universitatis Pekinensis

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Study on Applying Benzoquinones Reagent to the Determination of Dobotamine

ZHANG Shenghui, FENG Jianzhang, TONG Shenyang   

  1. Department of Chemistry, Peking University, Beijing, 100871
  • Received:1996-03-06 Online:1996-07-20 Published:1996-07-20

苯醌类试剂用于测定多巴酚丁胺的研究

张昇晖,冯建章,童沈阳   

  1. 北京大学化学系,北京,100871

Abstract: The charge transfer interactions of dobutamine with p-benzoquinone and chloranil were investigated in ethanol medium, the reactions of Dobutamine with p-benzoquinone and chloranil are complete. The products have maximum absorption at 500 nm and 472 nm, respectively. The apparent molar absorptivities are 1.81×104 for p-penzoquinone and 4.22×104 for chloranil. The method proposed on the basis of the above results was applied to the determination of Dobutamine injection and the results were satisfatory.

Key words: charge transfer reaction, benzoquinone, chloranil, spectrophotometry, dobutamine determination

摘要: 研究了多巴酚丁胺与对苯醌和四氯苯醌间的荷移反应。多巴酚丁胺与对苯醌和四氯苯醌间的反应均在乙醇介质中进行。络合物的最大吸收波长分别为500nm和472nm;表观摩尔吸光系数分别为1.81×104L·mol-1·cm-1和4.22×104L·mol-1·cm-1。用拟定的方法测定多巴酚丁胺制剂含量,获得满意结果。

关键词: 荷移反应, 对苯醌, 四氯对醌, 分光光度法, 多巴酚, 丁胺测定

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